Penetapan Kadar Nikotin pada Perokok Aktif di Kelurahan Duren Jaya Kecamatan Bekasi Timur

Authors

  • Laila Utari Zahra STIKes Mitra Keluarga
  • Elfira Maya Sari STIKes Mitra Keluarga
  • Ria Amelia STIKes Mitra Keluarga

DOI:

https://doi.org/10.62383/vimed.v3i1.2675

Keywords:

Active Smokers, GC-MS, Nicotine, Region, Urine

Abstract

Nicotine is the main chemical substance found in cigarettes and has toxic and addictive properties. Exposure to nicotine in active smokers can cause various health problems, including respiratory and cardiovascular disorders and dependence. The prevalence of active smokers in RT 08 RW 05, Duren Jaya Village, East Bekasi Subdistrict is quite high. However, data on nicotine levels in the bodies of active smokers remain very limited. This study aims to determine the nicotine levels in active smokers in Duren Jaya Village, RT 08 RW 05, Bekasi Timur District, using urine samples. The research method employs a descriptive design with a cross-sectional approach. Urine samples were collected from 30 male active smokers aged over 35 years who had smoked for at least 15 years. Nicotine levels were measured at the Jakarta Regional Health Laboratory using Gas Chromatography-Mass Spectrometry (GC-MS). Data were analyzed descriptively using SPSS version 22. The study included 30 male respondents (100%) with an average age of 41 years. The analysis results showed nicotine levels ranging from 59.908 ng/mLto 459.941 ng/mL, with the majority of respondents falling into the category of active smokers based on the biological threshold for nicotine levels. It can be concluded that the results obtained indicate that these levels correspond to active smokers using light tobacco.

References

Afolalu, E. F., Spies, E., Bacso, A., Clerc, E., Abetz-Webb, L., Gallot, S., & Chrea, C. (2021). Impact of tobacco and/or nicotine products on health and functioning: A scoping review and findings from the preparatory phase of the development of a new self-report measure. Harm Reduction Journal, 18(1), 1–16. https://doi.org/10.1186/s12954-021-00526-z

Aji, A., Maulinda, L., & Amin, S. (2015). Isolasi nikotin dari puntung rokok sebagai insektisida. Jurnal Teknologi Kimia Unimal, 4(1), 100–120. http://ft.unimal.ac.id/teknik_kimia/jurnal

Fernandes, A. G. O., Santos, L. N., Pinheiro, G. P., da Silva Vasconcellos, D., de Oliva, S. T., Fernandes, B. J. D., & Couto, R. D. (2020). Urinary cotinine as a biomarker of cigarette smoke exposure: A method to differentiate among active, second-hand, and non-smoker circumstances. The Open Biomarkers Journal, 10(1), 60–68. https://doi.org/10.2174/1875318302010010060

Hermawati, A. H., & Lathifah, Q. A. (2023). Faktor-faktor yang mempengaruhi kandungan nikotin dalam urine pada perokok aktif. Jurnal STIKES Hutama Abdi Husada Tulungagung, 1(1), 111–117.

Isnaeni, R., Inayati, N., Jiwantoro, Y. A., & Kristinawati, E. (2024). Gambaran nikotin pada pra lansia perokok linting (tembakau) di Desa Pohgading Timur Kecamatan Pringgabaya. Journal of Indonesia Laboratory Technology of Student (JILTS), 3(1), 1–5.

Kamelia, M., Marmanik, T. S., Satiyarti, R. B., Widiani, N., & Novitasari, A. (2022). Korelasi perilaku merokok dengan kesehatan masyarakat Desa Tegal Mukti. Jurnal Medika Malahayati, 6(1), 286–292. https://doi.org/10.33024/jmm.v6i1.6021

Kaparang, G. F., Mewoh, E., & Langingi, N. L. (2021). Persepsi perokok di masyarakat mengenai halangan berhenti merokok. Nutrix Journal, 5(2), 56. https://doi.org/10.37771/nj.vol5.iss2.583

Kementerian Kesehatan Republik Indonesia. (2019). Profil kesehatan Indonesia tahun 2019. Kementerian Kesehatan RI.

Khotimah, E., & Sun, N. N. (2022). Analisis kesalahan pada proses pra-analitik dan analitik terhadap sampel serum pasien di RSUD Budhi Asih. Jurnal Medika Hutama, 3(4), 402–406. http://jurnalmedikahutama.com

Lathifah, Q. A., Hermawati, A. H., & Putri, A. Y. (2020). Gambaran nikotin pada perokok pasif di Kabupaten Tulungagung. Borneo Journal of Medical Laboratory Technology, 3(1), 178–182. https://doi.org/10.33084/bjmlt.v3i1.1594

Murphy, S. E. (2021). Biochemistry of nicotine metabolism and its relevance to lung cancer. Journal of Biological Chemistry, 296, 100722. https://doi.org/10.1016/j.jbc.2021.100722

Nabilatus Sholikah, P., Mulyati, T. A., & Pujiono, F. E. (2022). Analisa cotinine pada urin perokok aktif dengan metode immunochromatography assay. Jurnal Sintesis, 2022(1), 43–48.

Onor, I. C. O., Stirling, D. L., Williams, S. R., Bediako, D., Borghol, A., Harris, M. B., Darensburg, T. B., Clay, S. D., Okpechi, S. C., & Sarpong, D. F. (2017). Clinical effects of cigarette smoking: Epidemiologic impact and review of pharmacotherapy options. International Journal of Environmental Research and Public Health, 14(10), 1147. https://doi.org/10.3390/ijerph14101147

Rosita, B., & Khairani, U. (2018). Analisis lama waktu pelayanan laboratorium di Rumah Sakit Umum Daerah Pasaman Barat. Jurnal Kesehatan Perintis, 5(1), 114–121. https://doi.org/10.33653/jkp.v5i1.153

Sanggu, E., & Wibowo, A. T. (2023). Faktor-faktor yang mempengaruhi kecenderungan merokok pada mahasiswa ilmu keolahragaan. Journal of Sport and Health, 4(2), 100–108.

Satria, M. A., Firdauzi, G. N., Syakuntala, W. D., & Kurnia, S. D. (2024). Kampanye pengelolaan limbah rokok untuk Kogarashi Coffee Bandung. ARS: Jurnal Seni Rupa dan Desain, 27(3), 189–198. https://doi.org/10.24821/ars.v27i3.7003

Septiani, R. (2022). Hubungan lama dan frekuensi merokok dengan kadar hemoglobin pada perokok aktif. Babul Ilmi: Jurnal Ilmiah Multi Science Kesehatan, 14(1), 30–40. https://doi.org/10.36729/bi.v14i1.809

Siagian, J. L. S., Pangaribuan, S., & Laudin, H. (2021). Faktor-faktor yang memengaruhi perilaku merokok pada tenaga kerja. Jurnal Inovasi Kesehatan, 3(1), 1–5.

Sihombing, R. P., Tamba, A. P., Renata, C. A., & Ngatin, A. (2022). Ekstraksi daun tembakau dengan metode MAE. Prosiding Industrial Research Workshop and National Seminar, 13(1), 807–812. https://doi.org/10.35313/irwns.v13i01.4171

Suharyanto, S., & Rahmadhani, A. S. (2023). Analysis of nicotine levels in Tingwe cigarette using ultraviolet-visible spectrophotometry. Pharmacon: Jurnal Farmasi Indonesia, 20(2), 104–109. https://doi.org/10.23917/pharmacon.v20i2.18332

Syafaat, M., & Safari, W. F. (2024). Rancang bangun alat pengisian volumetrik otomatis untuk penjaminan mutu laboratorium klinik. Jurnal Teknologi, 11(2), 2024–2160. https://doi.org/10.31479/jtek.v11i2.300

Syahraeni, H. K. H., & Rusman, A. D. P. (2022). Pengaruh paparan asap rokok di rumah terhadap kejadian hipertensi pada wanita. Jurnal Ilmiah Manusia dan Kesehatan, 5(2), 199–207. https://doi.org/10.31850/makes.v6i2.914

Tanti, D. A., Rachman, A., Taopik, O., Indrawati, A., Setyawati, W., & Nurlatifah, A. (2023). Konsentrasi gas NH₃ di daerah perkotaan. Jurnal Teknologi Lingkungan, 24(2), 143–148. https://doi.org/10.55981/jtl.2023.982

Theobald, S., Morgan, R., Hawkins, K., Ssali, S., George, A., & Molyneux, S. (2017). The importance of gender analysis in research for health systems strengthening. Health Policy and Planning, 32(Suppl. 5), v1–v3. https://doi.org/10.1093/heapol/czx163

Woen, A. W., & Sumbayak, E. M. (2024). Exposure to electric cigarette smoke (vape) on cerebrum and rat behavior: A literature review. Jurnal MedScientiae, 3(1), 36–42. https://doi.org/10.36452/jmedscientiae.v3i1.3209

Yudiana Shinta, D. (2018). Perbandingan toksisitas kandungan nikotin pada perokok aktif dan pasif. Prosiding Seminar Kesehatan Perintis, 1(2), 2622–2256.

Downloads

Published

2025-12-22

How to Cite

Laila Utari Zahra, Elfira Maya Sari, & Ria Amelia. (2025). Penetapan Kadar Nikotin pada Perokok Aktif di Kelurahan Duren Jaya Kecamatan Bekasi Timur. Vitalitas Medis : Jurnal Kesehatan Dan Kedokteran, 3(1), 257–269. https://doi.org/10.62383/vimed.v3i1.2675

Similar Articles

1 2 > >> 

You may also start an advanced similarity search for this article.