Phytochemical Constituents and Pharmacological Potential of Justicia gendarussa Burm. f.: A Review
DOI:
https://doi.org/10.62383/quwell.v2i2.2283Keywords:
Justicia Gendarussa, Male Contraceptive, Patentiflorin A, Pharmacology, PhytochemistryAbstract
Justicia gendarussa Burm. f., commonly known as gandarusa, is a medicinal shrub widely distributed in South and Southeast Asia. Traditionally, it has been used for treating rheumatism, headache, asthma, bronchitis, skin infections, and as a male contraceptive. Phytochemical analyses revealed the presence of alkaloids (gendarusin A, gendarusin B), flavonoids (quercetin, kaempferol, apigenin), saponins, tannins, phenolics, terpenoids, and Patentiflorin A, a compound with promising anti-HIV activity. Pharmacological investigations demonstrated its anti-inflammatory, analgesic, antimicrobial, antioxidant, antidiabetic, hepatoprotective, immunomodulatory, anticancer, and contraceptive potentials. This review highlights the phytochemical profile, pharmacological properties, and future prospects of J. gendarussa, emphasizing its potential as a phytopharmaceutical candidate. Further studies are required to standardize extracts, confirm clinical efficacy, and ensure long-term safety.
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