Recurrent Apthous Stomatitis (RAS) pada Mukosa Bibir Bawah yang Dipicu oleh Stress dan Kekurangan Zat Besi Tahap Awal

Authors

  • Safira Zahwa Anzali Universitas Muhammadiyah Surakarta
  • Sartari Entin Yuletnawati Universitas Muhammadiyah Surakarta

DOI:

https://doi.org/10.62383/quwell.v2i3.2242

Keywords:

Laboratory, Recurrent Apthous Stomatitis, Stress

Abstract

Recurrent aphthous stomatitis (RAS) is one of the most common oral mucosal diseases, characterized by recurrent and painful ulcerations of the mobile or non-keratinized oral mucosa. These lesions are often found on the tongue, labial, and buccal mucosa. Clinically, RAS is divided into three types: minor, major, and herpetiform. The minor type is the most common and has smaller lesions, while the major type has larger lesions and often leaves scars. The herpetiform type is characterized by numerous small lesions appearing simultaneously. Factors influencing the immunological response in RAS include genetic predisposition, viral and bacterial infections, food allergies, vitamin and microelement deficiencies, systemic diseases, stress, and hormonal disorders. Several studies have shown that these factors can trigger or worsen the occurrence of RAS lesions. In addition, emotional and physical stress can contribute to increasing the frequency or duration of ulceration. A 36-year-old female patient presented with pain on the inside of the lower lip that had lasted for 10 days. An intraoral examination revealed a unilateral, yellowish-white ulcer on the inner lower lip surrounded by a distinct, reddish erythema. The lesion was approximately 2-3 mm in size, single in size, soft in consistency, and symptomatic. Based on these findings, the treatment plan includes a complete blood count (CBC), which measures various blood components, including red blood cells, white blood cells, and platelets. This examination is necessary to obtain further information regarding the cause of RAS in this patient. RAS is a multifactorial lesion that can occur in the oral mucosa. Supportive tests such as a complete blood count (CBC) are very useful in establishing the diagnosis and providing further guidance in planning appropriate therapy. Appropriate medication is expected to help the patient recover from complaints and prevent recurrence.

 

Keywords : Recurrent Apthous Stomatitis, Laboratory, Stress

References

Arifin Turun 2 -- Rivera, Cesar. Essential of Recurrent Aphthous Stomatitis (Review). Jurnal Biomedical Reports, June 11, 2019, 11(2): 47- 50.doi.org/10.3892/br.2019.1221

Bukhari Ma, Aldossari Am, Alyami Im, Al Shari Ah, Al Huwaidi Aa, Alzaid Sy, Et Al. Pontic Design And Its Effects On The Health Of The Gingiva. Int J Community Med Public Health. 2022 Nov 28;9(12):4725. https://doi.org/10.18203/2394-6040.ijcmph20223238

Edgar, Natalie Rose., Miller, Richard A and Saleh, Dahlia. Recurrent aphthous stomatitis: a review.Journal of Clinical and Aesthetic Dermatology. 2017. 10(3): 26-16.

Fitriany J, Saputri AI. Anemia defisiensi besi. Jurnal. Kesehat Masy. 2018; 4(120200 5126):1-30. https://doi.org/10.29103/averrous.v4i2.1033

Ghosh, S., Nambiar, S., Patil, S., Haragannavar, V. C., Augustine, D., V,

Hamed Mortazavi, Hamed., Safi, Yaser., Baharvand, Maryam., dan Rahmani, Somayeh. Diagnostic Features of Common Oral Ulcerative Lesions: An Updated Decision Tree. Hindawi International Journal of dentistry. 2016. https://doi.org/10.1155/2016/7278925

Hamishehkar H, Nokhodchi A, Ghanbarzadeh S, Kouhsoltani M. Triamcinolone acetonide oromucoadhesive paste for treatment of aphthous stomatitis. Adv Pharm Bull. 2015;5(2):277-82. https://doi.org/10.15171/apb.2015.038

Mersil S, Pradono SA. Manifestasi klinis rongga mulut sebagai penanda awal penyakit iron deficiency anemia (IDA). J Ilm dan Teknol Kedokt Gigi. 2017; 13(2):1. Doi:10.32509/jitekgi.v13i2.842 https://doi.org/10.32509/jitekgi.v13i2.842

S. S. and Rao, R. S. 'Allergic and immunologic response of the oral mucosa: An overview', International Journal of Clinical Dental Sciences, 2016. 6(6), pp. 1-71.

Sari RK, Ernawati DS, Soebadi B. Recurrent aphthous stomatitis related to psychological stress, food allergy and gerd. ODONTO Dent J. 2019; 6: 45-51. https://doi.org/10.30659/odj.6.0.45-51

Seflin S, Nova A, Ratag BT. Hubungan antara asupan zat besi dan protein dengan kejadian anemia pada siswi SMP Negeri 10 Manado. Pharmacon. 2015;4(4): 191-7. Doi:10.35799/pha.4.2015.10239

Setiadhi R, Firman DR. Obat di bidang penyakit mulut dan penulisan resepnya. Bandung: Unpad Press; 2017. p. 1-61.

Shhsavarani, Amir Mohammad, Abadi, Marz E A., and Kalkhoran, Maryam Hakimi. Stress: Facts and Theories through Liaterature Review. International Journal of Medical Reviews. 2015. 2(2) : 231-241

Slebioda z, zsponar e, kowalska a. Etiopathogenesis of recurrent apthous stomatitis and the role of immunologic aspects : a literature review. Arch immunol ther exp. 2014. 63:205- 215 https://doi.org/10.1007/s00005-013-0261-y

Downloads

Published

2025-08-19

How to Cite

Safira Zahwa Anzali, & Sartari Entin Yuletnawati. (2025). Recurrent Apthous Stomatitis (RAS) pada Mukosa Bibir Bawah yang Dipicu oleh Stress dan Kekurangan Zat Besi Tahap Awal. Quantum Wellness : Jurnal Ilmu Kesehatan, 2(3), 28–34. https://doi.org/10.62383/quwell.v2i3.2242