Case Report : Eritema Nodosum Leprosum pada Pasien Pasca Terapi Kusta Tipe MB dengan Kecacatan Tingkat 2

Authors

  • Mohamad Mimbar Topik Universitas Malikussaleh
  • Mumtaz Alvira Universitas Malikussaleh

DOI:

https://doi.org/10.62383/ikg.v2i3.2206

Keywords:

Erythema Nodosum Leprosum, Cough With Phlegm, Immune, MB

Abstract

Erythema nodosum leprosum (ENL) is a type 2 leprosy reaction caused by the humoral immune response of Mycobacterium leprae, which results in inflammatory nodules on the skin that can lead to nerve and organ damage. One of the immune-mediated complications of leprosy and severe multisystem lepromatous leprosy is known as type 2 leprosy reaction or erythema nodusum leprosum (ENL). Risk factors for ENL can be influenced by age, educational attainment, socioeconomic status, and gender. ENL causes high morbidity and mortality and usually requires immediate medical attention. We report a case of ENL with grade 2 disability in a clinically diagnosed Multibacillary (MB) leprosy patient who had had leprosy for 20 years.

References

Annisa, G., & Khairani, R. (2024). Rokok dan alergi berhubungan dengan bronkitis akut pada pasien dewasa. Jurnal Akta Trimedika, 1(3), 316–326.

Bela, A. (2023). Anatomi dan fisiologi sistem respirasi manusia. Projek IPAS.

Bhatta, D. N., & Glantz, S. A. (2020). Association of e-cigarette use with respiratory disease among adults: A longitudinal analysis. American Journal of Preventive Medicine, 58(2), 182–190.

Braymiller, J. L., Barrington-Trimis, J. L., Leventhal, A. M., Islam, T., Kechter, A., Krueger, E. A., Cho, J., Lanza, I., Unger, J. B., & McConnell, R. (2020). Assessment of nicotine and cannabis vaping and respiratory symptoms in young adults. JAMA Network Open, 3(12), e2030189. https://doi.org/10.1001/jamanetworkopen.2020.30189

Fabanyo, R. A., Solikhah, M., Yusuf, F. F., & Sairmau, G. T. (2024). Hubungan merokok dan paparan polusi dengan penyakit bronkhitis di RSUD Kabupaten Sorong: Merokok dan paparan polusi. Nursing Arts, 18(2), 160–167.

Kalhan, R., Dransfield, M. T., Colangelo, L. A., Cuttica, M. J., Jacobs, D. R., Jr., Thyagarajan, B., Estepar, R. S. J., Harmouche, R., Onieva, J. O., & Ash, S. Y. (2018). Respiratory symptoms in young adults and future lung disease: The CARDIA Lung Study. American Journal of Respiratory and Critical Care Medicine, 197(12), 1616–1624.

Killeen, B. M., & Wolfson, A. B. (2020). Antibiotics for acute bronchitis. American Family Physician, 102(9), Online.

Lai, K., Shen, H., Zhou, X., Qiu, Z., Cai, S., Huang, K., Wang, Q., Wang, C., Lin, J., Hao, C., Kong, L., Zhang, S., Chen, Y., Luo, W., Jiang, M., Xie, J., & Zhong, N. (2018). Clinical practice guidelines for diagnosis and management of cough—Chinese Thoracic Society (CTS) Asthma Consortium. Journal of Thoracic Disease, 10(11), 6314–6351. https://doi.org/10.21037/jtd.2018.09.153

Morley, V. J., Firgens, E. P. C., Vanderbilt, R. R., Zhou, Y., Zook, M., Read, A. F., & MacGeorge, E. L. (2020). Factors associated with antibiotic prescribing for acute bronchitis at a university health center. BMC Infectious Diseases, 20, 1–14.

Mustofa, S., & Patongai, F. M. R. (2023). Bronkitis akibat kerja: Patogenesis, diagnosis, penatalaksanaan dan pencegahan. Jurnal Kesehatan dan Agromedicine, 10(2), 27–38.

Pulia, M., Redwood, R., & May, L. (2018). Antimicrobial stewardship in the emergency department. Emergency Medicine Clinics of North America, 36(4), 853–872. https://doi.org/10.1016/j.emc.2018.06.012

Saust, L. T., Siersma, V., Lykkegaard, J., Bjerrum, L., & Hansen, M. P. (2022). Diagnosis and antibiotic treatment of urinary tract infections in Danish general practice: A quality assessment. Antibiotics, 11(12), 1759. https://doi.org/10.3390/antibiotics11121759

Singh, A., Avula, A., & Zahn, E. (2025). Acute bronchitis. StatPearls Publishing.

Smith, M. P., Lown, M., Singh, S., Ireland, B., Hill, A. T., Linder, J. A., Irwin, R. S., Adams, T. M., Altman, K. W., & Azoulay, E. (2020). Acute cough due to acute bronchitis in immunocompetent adult outpatients: CHEST Expert Panel Report. Chest, 157(5), 1256–1265.

Warlem, N., Triansyah, I., Khudri, G., Handayani, K. M., & Halimah, S. (2023). Hubungan riwayat kebiasaan merokok dengan kejadian bronkitis di Puskesmas Muarasipongi tahun 2019–2020. Nusantara Hasana Journal, 3(4), 110–117.

Wilson, M., & Wilson, P. J. K. (2021). Acute bronchitis. In Close encounters of the microbial kind: Everything you need to know about common infections (pp. 253–260).

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Published

2025-07-15

How to Cite

Mohamad Mimbar Topik, & Mumtaz Alvira. (2025). Case Report : Eritema Nodosum Leprosum pada Pasien Pasca Terapi Kusta Tipe MB dengan Kecacatan Tingkat 2. Inovasi Kesehatan Global, 2(3), 161–168. https://doi.org/10.62383/ikg.v2i3.2206